PROtrol™ SARS-CoV-2 Lineage BA.5; Omicron Variant (Isolate: USA/COR-22-063113/2022) (1 mL)
- Volume: 1.0mL
- Units/Pack: 1
- Storage Condition: -65°C or below
- Hazardous Information: Non-Infectious
- Product Type: Inactivated Organism
Description
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), isolate hCoV- 19/USA/COR-22-063113/2022 was isolated from a human in May 2022, in Memphis, Tennessee, USA. Under the nomenclature system introduced by GISAID (Global Initiative on Sharing All Influenza Data), SARS-CoV-2, isolate hCoV-19/USA/COR-22- 063113/2022 is assigned lineage BA.5 using the Phylogenetic Assignment of Named Global Outbreak lineages (PANGO) tool. It was labeled as an Omicron variant by the World Health Organization (WHO).
SARS-CoV-2 was propagated in VeroE6 cells. The viral culture fluid was clarified via centrifugation to remove cellular debris prior to inactivation.
PROtrol™ (Protein control) is formulated with viral particles that have been modified to render them non-infectious. Each vial contains 1.0 mL of SARS- CoV-2 PROtrol™ frozen in 2% MEM media.
The pre-inactivation titer was determined from an infectious aliquot. Each lot of PROtrol™ is tested using an N-protein ELISA developed internally at ZeptoMetrix.
Viral inactivation is verified by the absence of viral growth in tissue culture-based infectivity assay
