SARS-CoV-2 Panels & Controls for Coronavirus Testing Quality Control, Research, and Assay Development

Coronaviruses (CoV) are common throughout the world and are part of a large family of viruses that cause illnesses ranging from the common cold to the Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Today we are faced with SARS-CoV-2 which is rapidly spreading itself globally.

The potential global health risk posed by SARS-CoV-2 is extremely high as the influenza-like illness ranges from mild symptoms to severe illness and possible death. Current confirmed cases are seeing prolific growth daily and CDC recommendations for infection prevention and control is evolving quickly.

As we strive to better understand SARS-CoV-2 and look forward to providing developers and laboratories with safe to use, non-infectious external quality controls, we recommend a review of our current Coronavirus products which may provide some utility in your assay development and/or research and analytical studies.


  • NATtrol molecular Controls are non-infectious, ready-to-use, whole organisms which are designed to evaluate performance of molecular tests. They can be used for verification of assays, training of laboratory personnel and to monitor assay-kit lot performance.

  • Heat-inactivated viral culture fluids are designed for molecular based testing.

  • Purified heat-inactivated lysates are intended for research, product development, manufacturing, and quality assurance testing. Viral lysates can be used as an antigen, as a source for the purification of viral proteins, or in assays for the detection of viral antibodies.
Organism / Strain Part Number Product Description Classification
SARS-CoV-2
 
Multiple Target/Variant Panels  
Coronavirus 229E, Coronavirus HKU-1, Coronavirus NL63, Coronavirus OC43, SARS-CoV-2: USA-WA1/20204, Adenovirus 3, B. pertussis, C. pneumoniae, Influenza A 2009 H1N1pdm, Influenza A H1N1, Influenza A H3N2, Influenza B, M. pneumoniae, Metapneumovirus 8, Parainfluenza virus 1, Parainfluenza virus 2, Parainfluenza virus 3, Parainfluenza virus 4, Rhinovirus 1A, RSV A, Negative NATRVP2-QIA

NATtrol Respiratory Verification Panel 2 (21 x 0.25 mL)

Qualitative controls

RUO

SARS-CoV-2: USA-WA1/2020, Coronavirus 229E, Coronavirus HKU-1, Coronavirus NL63, Coronavirus OC43, Adenovirus 1, Adenovirus 3, Adenovirus 31, B. parapertussis, B. pertussis, C. pneumoniae, Influenza A 2009 H1N1pdm, Influenza AH1, M. pneumoniae, Parainfluenza 1, Parainfluenza 4, Rhinovirus 1A, Influenza B, Parainfluenza 2, Parainfluenza 3, RSV A, Influenza A H3N2, Metapneumovirus 8, Negative NATRVP2.1-BIO

NATtrol Respiratory Verification Panel 2.1 (24 x 0.6 mL)

Qualitative controls

RUO

SARS-CoV-2: USA-WA1/2020, Coronavirus 229E, Coronavirus HKU-1, Coronavirus NL63, Coronavirus OC43, Adenovirus 1, Adenovirus 3, Adenovirus 31, B. parapertussis, B. pertussis, C. pneumoniae, Influenza A 2009 H1N1pdm, Influenza AH1, M. pneumoniae, Parainfluenza 1, Parainfluenza 4, Rhinovirus 1A, Influenza B, Parainfluenza 2, Parainfluenza 3, RSV A, Influenza A H3N2, Metapneumovirus 8, Negative NATRPC2.1-BIO

NATtrol Respiratory Panel 2.1 Controls (12 x 0.3 mL)

Qualitative controls

RUO

Alpha (B.1.1.7) England/204820464/2020; Beta (B.1.351) South Africa/ KRISP-K005325/2020; Delta (B.1.617.2) USA/PHC658/2021;
Gamma (P.1) Japan/TY7-503/2021
NATSARS(COV2)-VP

NATtrol SARS-CoV-2 Variant Panel (4 x 0.5mL)
Target concentration: 50,000 copies/mL

Quantitative controls

RUO

Omicron B.1.1.529  
B.1.1.529 BA.1: Isolate: USA/MD-HP20874/2021 NATCOV2(OMC)-ERC NATtrol SARS-CoV-2 Omicron External Run Control (6 x 0.5 mL)
Target concentration: 50,000 copies/mL
RUO
B.1.1.529 BA.1: Isolate: USA/MD-HP20874/2021 0810642CFHI SARS-CoV-2 Omicron Heat-Inactivated CF (1 mL) RUO
B.1.1.529 BA.2: Isolate: USA/MD-HP24556/2022 0810643CFHI SARS-CoV-2 Omicron Heat-Inactivated CF (1 mL) RUO
USA-WA1/2020  
SARS-COV-2: USA-WA1/2020, Influenza A: A/Brisbane/10/07,
Influenza B: B/Florida/02/06, RSVB: CH93(18)-18
NATFRC-6C

NATtrol Flu/RSV/SARS-CoV-2 Positive Control (6 x 0.5 mL)

To be used with NATCV9-6C

RUO

SARS-COV-2: USA-WA1/2020, Influenza A: A/Brisbane/10/07,
Influenza B: B/Florida/02/06, RSVB: CH93(18)-18
NATFRC-6C-IVD NEW

NATtrol Flu/RSV/SARS-CoV-2 Positive Control (6 x 0.5 mL)

To be used with NATCV9-6C-IVD

CE IVD

SARS-COV-2: USA-WA1/2020, Influenza A: A/Brisbane/10/07,
Influenza B: B/Florida/02/06, RSVB: CH93(18)-18
NATFRC-ERC NEW NATtrol Flu/RSV/SARS-CoV-2 External Run Control (6 x 0.5 mL)
Target concentration: 15,000 copies/mL
RUO
Isolate: USA-WA1/2020 NATSARS(COV2)-ST NATtrol SARS-CoV-2 Stock
Target concentration: 1,000,000 copies/mL
RUO
Isolate: USA-WA1/2020 NATSARS(COV2)-ERC NATtrol SARS-CoV-2 External Run Control (6 x 0.5 mL)
Target concentration: 50,000 copies/mL
RUO
Isolate: USA-WA1/2020 NATSARS(COV2)-ERC-IVD      NATtrol SARS-CoV-2 External Run Control (6 x 0.5 mL)
Target concentration: 50,000 copies/mL
CE IVD
Isolate: USA-WA1/2020 NATSARS(COV2)-ERC1 NATtrol SARS-CoV-2 External Run Control (6 x 1.0 mL)
Target concentration: 50,000 copies/mL
RUO
Isolate: USA-WA1/2020 NATSARS(COV2)-ERC1-IVD NATtrol SARS-CoV-2 External Run Control (6 x 1.0 mL)
Target concentration: 50,000 copies/mL
CE IVD
Isolate: USA-WA1/2020 0810587 SARS-CoV-2 Lysate (1 mg) RUO
Isolate: USA-WA1/2020 0810587-0.5mg SARS-CoV-2 Lysate (0.5 mg) RUO
Isolate: USA-WA1/2020 0810587CFHI-0.5mL SARS-CoV-2 Heat-Inactivated CF (0.5 mL) RUO
Isolate: USA-WA1/2020 0810587CFHI SARS-CoV-2 Heat-Inactivated CF (1 mL) RUO
Italy-INMI1  
Isolate: Italy-INMI1 0810589CFHI SARS-CoV-2 Heat-Inactivated CF (1 mL) RUO
Hong Kong/VM20001061/2020  
Isolate: Hong Kong/VM20001061/2020 0810590CFHI SARS-CoV-2 Heat-Inactivated CF (1 mL) RUO
USA/NY-Wadsworth-103677-01/2020      
B.1_2020: Isolate: USA/NY-Wadsworth-103677-01/2020 0810621CFHI SARS-CoV-2 Heat-Inactivated CF (1 mL) RUO
USA/NY-Wadsworth-33126-01/2020      
B.1.595_2020: Isolate: USA/NY-Wadsworth-33126-01/2020 0810622CFHI SARS-CoV-2 Heat-Inactivated CF (1 mL) RUO
Alpha B.1.1.7  
B.1.1.7: Isolate: England/204820464/2020 NATSARS(COV2-UK)-ST NATtrol SARS-CoV-2 Alpha Stock (1 mL)
Target concentration: 1,000,000 copies/mL
RUO
B.1.1.7: Isolate: England/204820464/2020 0810614CFHI SARS-CoV-2 Alpha Heat-Inactivated CF (1 mL) RUO
B.1.1.7: Isolate: USA/CA_CDC_5574/2020 0810612CFHI SARS-CoV-2 Alpha Heat-Inactivated CF (1 mL) RUO
Beta B.1.351  
B.1.351: Isolate: South_Africa/KRISP-K005325/2020 NATSARS(COV2-SA)-ST NATtrol SARS-CoV-2 Beta Stock (1 mL)
Target concentration: 1,000,000 copies/mL
RUO
B.1.351: Isolate: South_Africa/KRISP-K005325/2020 0810613CFHI SARS-CoV-2 Beta Heat-Inactivated CF (1 mL) RUO
Gamma P1  
P1: Isolate: Japan/TY7-503/2021 0810616CFHI SARS-CoV-2 Gamma Heat-Inactivated CF (1 mL) RUO
P1_2021: Isolate: NY-Wadsworth-21033899-01/2021 0810617CFHI SARS-CoV-2 Gamma Heat-Inactivated CF (1 mL) RUO
Zeta P2  
P2_2021: Isolate: NY-Wadsworth-21006055-01/2021 0810618CFHI SARS-CoV-2 Zeta Heat-Inactivated CF (1 mL) RUO
Iota B.1.526  
B.1.526_2021: Isolate: USA/NY-Wadsworth-21025952-01/2021 Isolate 1 0810619CFHI SARS-CoV-2 Iota Heat-Inactivated CF (1 mL) RUO
B.1.526_2021: Isolate: USA/NY-Wadsworth-21018781-01/2021 Isolate 2 0810620CFHI SARS-CoV-2 Iota Heat-Inactivated CF (1 mL) RUO
Kappa B.1.617.1  
B.1.617.1: Isolate: USA/CA-Stanford-15_S02/2021 0810623CFHI SARS-CoV-2 Kappa Heat-Inactivated CF (1 mL) RUO
Delta B.1.617.2  
B.1.617.2: Isolate: USA/PHC658/2021 0810624CFHI SARS-CoV-2 Delta Heat-Inactivated CF (1 mL) RUO
Negative Controls  
Coxsackievirus A9 NATCV9-6C

NATtrol Flu/RSV/SARS-CoV-2 Negative Control (6 x 0.5 mL)

To be used with NATFRC-6C

RUO

Coxsackievirus A9 NATCV9-6C-IVD NEW

NATtrol Flu/RSV/SARS-CoV-2 Negative Control (6 x 0.5 mL)

To be used with NATFRC-6C-IVD

CE IVD

VeroE6 cells 0820010CFHI SARS-CoV-2 Heat-Inactivated CF Negative control (1 mL) RUO
A-549 cells NATSARS(COV2)-NEG NATtrol Negative Control (6 x 0.5 mL)
Target concentration: 50,000 cells/mL
RUO
A-549 cells NATSARS(COV2)-NEG-IVD NATtrol Negative Control (6 x 0.5 mL)
Target concentration: 50,000 cells/mL
CE IVD
A-549 cells NATSARS(COV2)-NEG1 NATtrol Negative Control (6 x 1.0 mL)
Target concentration: 50,000 cells/mL
RUO
A-549 cells NATSARS(COV2)-NEG1-IVD NATtrol Negative Control (6 x 1.0 mL)
Target concentration: 50,000 cells/mL
CE IVD
SARS  
2003-00592 NATSARS-ST NATtrol Coronavirus Stock (1 mL) RUO
 
Seasonal Coronavirus  
229E  
229E NATCOV(229E)-ST NATtrol Coronavirus Stock (1 mL)
Target ct range: 22–25
RUO
229E 0810229CF Coronavirus CF (1 mL) RUO
229E 0810229CFHI Coronavirus Heat-Inactivated CF (1 mL) RUO
229E 0810229 Coronavirus Lysate (1 mg) RUO
NL63  
NL63 NATCOV(NL63)-ST NATtrol Coronavirus Stock (1 mL)
Target ct range: 22–25
RUO
NL63 0810228CF Coronavirus CF (1 mL) RUO
NL63 0810228CFHI Coronavirus Heat-Inactivated CF (1 mL) RUO
NL63 0810228 Coronavirus Lysate (1 mg) RUO
OC43  
OC43 0810024CF Coronavirus CF (1 mL) RUO
OC43 0810024CFHI Coronavirus Heat-Inactivated CF (1 mL) RUO
OC43 0810024 Coronavirus Lysate (1 mg) RUO
MERS-CoV  
Florida/USA-2_Saudi Arabia_2014 NATMERS-ST NATtrol MERS-CoV Stock (1 mL)
Target ct range: 22–28
RUO
Florida/USA-2_Saudi Arabia_2014 US sales only 0810575CFHI MERS-CoV Heat-Inactivated CF (1 mL) RUO

 

 

 

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