Per and Polyfluoroalkyl Substance (PFAS) Reference Materials

PFAS regulations are becoming increasingly stringent, putting pressure on testing laboratories to stay ahead. From environmental testing to human exposure monitoring, the complexity of PFAS compounds demands reliable methods and reference materials. Whether analysing trace levels in water, soil, or biological samples, accuracy starts with dependable PFAS reference materials from the Chiron product line.

What Are PFAS and Why They're Under Scrutiny

PFAS are a large class of synthetic chemicals known for their stability—and their staying power. Used in everything from firefighting foam to nonstick coatings, these compounds resist heat, water, and degradation, which also means they tend to accumulate in the environment and in living systems.

That persistence is exactly why PFAS have drawn global attention. Studies link long-term exposure to potential health risks, prompting waves of new PFAS regulations aimed at tighter limits and stricter testing. For labs working in environmental science, toxicology, or industrial monitoring, that shift means adapting fast with tools that meet changing expectations.

Challenges in PFAS Analysis

PFAS analysis isn't straightforward. With thousands of structurally similar compounds, many found at trace levels, labs face a real challenge in detection, quantification, and consistency. These substances often slip through standard workflows, especially in complex matrices like soil, serum, or wastewater.

Reliable PFAS analytical methods depend on precise calibration, contamination control, and high-purity standards. Whether you're working with targeted LC-MS/MS protocols or expanding your PFAS analysis method to cover emerging compounds, even small deviations can throw off results. That's why validated reference materials like the Chiron product line at ZeptoMetrix's collection matter, because accurate data starts with stable, traceable inputs.

Product Offerings

Chiron provides a focused portfolio of PFAS research chemicals and certified reference materials built for labs that demand precision. Our materials support quantitative PFAS analysis across numerous matrices, like drinking water, soil, serum, and more, with options that slot easily into validated workflows.

We manufacture each product under strict quality systems to ensure consistency and reproducibility. Whether you're expanding your PFAS analysis method or maintaining compliance with evolving standards, our perfluoroalkyl reference materials are available in liquid or lyophilized formats, ready for LC-MS/MS and other targeted platforms.

Applications Across Research and Regulatory Environments

As PFAS regulations continue to evolve, labs are under pressure to deliver results that hold up to scrutiny. Chiron PFAS reference materials are vital in numerous applications where accuracy matters just as much as speed.

You'll find our materials supporting:

• Environmental testing for regulatory reporting and contamination studies
• Occupational exposure monitoring in industrial and manufacturing settings
• Toxicological research focused on bioaccumulation and long-term health impacts
• Method validation and proficiency testing to meet new PFAS analysis method requirements

Whether you're running targeted screens or pushing into new compound classes, our products help keep your workflows aligned with real-world demands.

Built to Meet Analytical and Regulatory Demands

PFAS testing isn’t getting simpler, and regulatory expectations aren’t getting looser. As an ISO 17034-certified reference material producer, we test our materials in an ISO/IEC 17025-accredited facility, so you get reference materials that meet the same standards your lab is held to.

Each product has full documentation and traceability to support method validation, internal QA/QC, and external audits. Whether you’re working under EPA guidelines, EU directives, or regional PFAS regulations, our materials will slot into compliant workflows without slowing you down.

Frequently Asked Questions About PFAS Reference Materials

Chiron fields numerous questions as we work with labs across environmental, industrial, and research settings. Here are some common things people want to know.